Take you to understand Natamycin


Natamycin is a nearly white or cream-yellow crystalline powder. It is an odorless, tasteless, low-dose, and highly safe food preservative. Natamycin is a white to milky white odorless and tasteless crystalline powder prepared by controlled fermentation of Streptomyces data. It usually exists as an enol structure. Its mechanism of action is to combine with fungal ergosterol and other sterol groups to inhibit the biosynthesis of ergosterol, thereby to cause cell membrane distortion, eventually leading to leakage and cell death.

The ionization constant: Natamycin is an amphoteric substance with pKa values of 4.6 and 8.35, and its isoelectric point is 6.5
Melting point: 280℃
Solubility: It is slightly soluble in water, hardly soluble in most organic solvents. The solubility in water at room temperature is 30~100mg/L. When the pH is lower than three or higher than 9, its solubility will increase, but it will reduce the stability of natamycin.

In June 1982, the US FDA officially approved natamycin as a food preservative. In 1996, the Chinese Food Additive Standard Chemical Technical Committee officially approved natamycin as a food preservative. The FAO/WHO Joint Expert Committee on Food Additives stipulates that the human body can unconditionally accept an intake of 0.3 mg of natamycin per kilogram of body weight per day. JECFA/EC also authorized the approval. The human body usually consumes much less than the safe amount, even for cheeses and sausages consumed in large amounts.


Natamycin is a natural antifungal compound produced by the fermentation of Streptomyces. It belongs to the polyene macrolides. It can not only inhibit the growth of various molds and yeasts but also inhibit mycotoxins ( Toxins produced by molds cannot be decomposed prior to the use of Natamycin ). Therefore, it can be widely used in food preservation and antifungal treatment. Natamycin has no inhibitory effect on bacteria, so it does not affect the natural maturation process of yogurt, cheese, raw ham, and dried sausage.

Baoding faithful Industry Co., Ltd. produces professional natamycin, exported to Europe, America, Asia, and other countries. It has comprehensive inspection and testing certificates, stable supply, fast delivery, and provides you with professional knowledge on the premises of the sale. , Provide you with professional tracking and guarantee after purchase, and we look forward to cooperating with you.


To learn more about this product, click here ↓