What is hyaluronic acid
Hyaluronic acid (HA) is a mucopolysaccharide composed Of repeated disaccharide units of glucuronic acid and N-acetylglucosamine. The commercial HA is commonly a sodium form, called Sodium hyaluronate. HA is widely presents in the extracellular matrix of animal tissues and vitreous humor. Its main physiological function is water retention and lubrication.
The origin of hyaluronic acid
In 1934, Karl Meyer and his assistant John Palmer first announced the discovery of HA. They purified HA from bovine vitreous and showed that it contained a hexuronic acid and a hexosamine. They proposed “for convenience, the name hyaluronic acid, from hyaloid (vitreous) + uronic acid.” Up to the mid-1940s, HA had been isolated successfully from other sources- synovial fluid, skin, umbilical cord, cock’s comb, etc.
From 1980s, microbial fermentation method is used in commerical production. Now hyaluronic acid is widely used in cosmetic, health food and pharmaceutical fields.
The manufacturing process
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- Cosmetic grade hyaluronic acid( sodium hyaluronate) admin 2017-10-31T08:11:27+00:00
- Pharmaceutical grade hyaluronic acid( sodium hyaluronate) admin 2017-10-31T08:13:07+00:00