Application of isoleucine


Isoleucine is one of eight essential amino acids and one of the three branched-chain amino acids. It occupies a critical position in human liver metabolism. Together with isoleucine and valine, it can repair muscles, control blood sugar, and Provide energy to body tissues. L-isoleucine is nutritionally related to valine and leucine, similar in structure. Although it is a carbohydrate amino acid, it has a slight ketogenic effect.

The main application of isoleucine

L-isoleucine is an essential amino acid for the human body and one of the three branched-chain amino acids. Because of its particular structure and function, it occupies a critical position in human liver metabolism. If the human body is short of L-isoleucine for a long time, it will affect its physiological functions, leading to metabolic disorders and decreased resistance. There are two asymmetric carbon atoms in isoleucine, so there are four stereoisomers.

1. Amino acid drugs

It is a nutritional supplement mixed with other carbohydrates, inorganic salts, and vitamins for injection. Compatible with other amino acids, it is used in amino acid infusion and preparation, such as: formulating compound amino acid preparations-nutrition fortifiers, primarily used in high branched-chain amino acid infusion (such as 3H infusion, etc.), oral liquid (ganan dry syrup, etc.).

Adverse reactions and contraindications: The supplemented isoleucine and other amino acids are required to maintain an appropriate ratio when increasing amino acids. However, excessive consumption will antagonize leucine, hinder development, cause the consumption of other amino acids, and negative nitrogen balance.

2. Food additives

One of the essential amino acids, it can fortify various foods. For example, the isoleucine in wheat flour, gluten, peanut flour, potatoes, etc., is a restricted amino acid and should be fortified.

3. Nutritional supplements

Isoleucine is a branched-chain amino acid. The human body shares three branched-chain amino acids (BCAA), valine, leucine, and isoleucine, and they work together to promote muscle recovery after exercise and provide energy to body tissues. Therefore, if you follow a low-protein diet and exercise a lot, you should consider the first choice of health products.

4. This product is also used in biochemical research, bacteriology, and tissue culture.