What is pancreatin?

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What is pancreatin?

Applications of enzyme preparations

Enzyme preparations are currently one of the most effective nutritional supplements available. Enzymes are molecules that can speed up the chemical reaction – they can help generate new molecules, break the molecules that link molecules together, and divide them into smaller units. Most of the enzyme products usually contain digestive enzymes extracted from porcine pancreatic (pancreatic juice), fungi, or plant sources. The function of these enzymes and human pancreas secretion of digestive enzymes function is very similar. It has been found that enzyme preparations can be used in the following cases:

Cancer digestion support
Hepatitis C, herpes, herpes zoster
Inflammation, sports injuries and trauma
Pancreatic insufficiency
food allergy
Multiple sclerosis
Rheumatoid arthritis and other autoimmune diseases

pancreatin

What is the pancreas? pancreatin

The pancreas is a digestive organ in the abdominal cavity, located below the

stomach. Its main job is to produce the enzymes needed for food digestion

and absorption. Secreted enzymes include lipases that can digest fat,

proteases that digest proteins, and amylases that secrete starch molecules.

Does taking pancreatin really promote digestion?

Yes. In fact, traditional medicine has been used in pancreatic insufficiency and cystic fibrosis (a rare genetic disease) using trypsin preparations to help digestion. Symptoms of pancreatic insufficiency are indigestion, malabsorption, malnutrition, and abdominal discomfort.

Why can pancreatin be used as natural anti-inflammatory drugs?

Proteases are important for preventing tissue damage and fibrin clot formation during inflammation. Protease can cause fibrin to accelerate the decomposition, the process of fibrinolysis. Fibrin in the process of inflammation will be in the inflammatory area around the formation of a wall, which will block the blood vessels and lymphatic vessels, leading to swelling. Fibrin can also cause blood clot formation, blood clots may be displaced and cause stroke or heart disease.

pancreatin

It has been found that pancreatin and protease preparations are very effective in the treatment of many severe chronic inflammatory symptoms, including sports injuries, tendinitis, rheumatoid arthritis. In addition to being used as an antiinflammatory drug to treat wounds and inflammation, pancreatin is also commonly used to treat thrombophlebitis, which can cause blood clots to be generated, inflamed, displaced and cause stroke or heart disease in the veins.

If I need to take pancreatin, how can I judge his effectiveness?

Pancreatin products are quite common as a nutritional supplements. Most commercial preparations are prepared from fresh pig pancreas. The USP (USP) sets a strict definition of its activity level. 1x pancreatin products contain amylase activity of not less than 25 USP units per milliliter, not less than 2.0 USP units of lipase activity, and no less than 25 USP units of protease activity.

The higher potency is marked with a multiple of an integer to indicate its intensity. For example, a highly effective, undiluted pancreatic juice extract that is 10 times stronger than the USP standard will be designated as 10X USP. People prefer high-potency products that are superior to less potent pancreatic products because low-potency products are usually diluted with brine, lactose, or glucose to achieve the desired strength (eg 4X or 1X).

pancreatin

Is the Pancreatin preparation safe?

Pancreatic extract is usually well tolerated and does not cause significant side effects. Even those who are considered normal pancreatic function, taking pancretin will not produce serious side effects, nor will they reduce their ability to generate pancreatin. However, my suggestion is to use these preparations only when there is a clear need.

Name CAS Number HS Code EINECS Number Specifications
Pancreatin
8049-47-6
3507909000
232-468-9
Pancreatin 4 x USP
Pancreatin 8 x USP
Pancreatin 10 x USP

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References

1.Rubinstein E, et al.: Antibacterial activity of the pancreatic fluid. Gastroenterol 1985;88:927-32.
2. Ambrus JL, et al.: Absorption of exogenous and endogenous proteolytic enzymes. Clin Pharmacol Therap 1967;8:362-8.
3. Kabacoff BB, et al.: Absorption of chymotrypsin from the intestinal tract. Nature 1963;199:815-7.
4. Martin GJ, et al.: Further in vivo observations with radioactive trypsin. Am J Pharm 1964;129:386-92.
5. Avakian S: Further studies on the absorption of chymotrypsin. Clin Pharmacol Therap 1964;5:712-5.
6. Liebow C and Rothman SS: Enteropancreatic circulation of digestive enzymes. Science 1975;189:472-4.
7. Oelgoetz AW, et al.: The treatment of food allergy and indigestion of pancreatic origin with pancreatic enzymes. Am J Dig Dis Nutr 1935;2:422-6.
8. Carroccio A, et al.: Pancreatic enzyme therapy in childhood celiac disease. A double-blind prospective randomized study. Dig Dis Sci 1995;40:2555-2560.
9. Innerfield I: Enzymes in Clinical Medicine. McGraw Hill, New York, 1960.
10. Mazurov VI, et al. Beneficial effects of concomitant oral enzymes in the treatment of rheumatoid arthritis. Int J Tiss React 1997;19:91.
11. Ransberger K: Enzyme treatment of immune complex diseases. Arthritis Rheuma 1986;8:16-9.
12. Steffen C, et al.: Enzyme therapy in comparison with immune complex determinations in chronic polyarteritis. Rheumatologie 1985;44:51-6.
13. Ransberger K and van Schaik W: Enzyme therapy in multiple sclerosis. Der Kassenarzt 1986;41:42-5.
14. Gonzalez NJ and Isaacs LL: Evaluation of pancreatic proteolytic enzyme treatment of adenocarcinoma of the pancreas, with nutrition and detoxification
support. Nutr Cancer 1999;33:117-24.
15. Leipner J and Saller R: Systemic enzyme therapy in oncology: effect and mode of action. Drugs. 2000;59:769-80.
16. Kleine MW, Stauder GM and Beese EW: The intestinal absorption of orally administered hydrolytic enzymes and their effects in the treatment of
acute herpes zoster as compared with those of oral acyclovir therapy. Phytomedicine 1995;2:7-15.
17. Kabil SM and Stauder G: Oral enzyme therapy in hepatitis C patients. Int J Tiss React 1997;19:97-8.
18. Schneider, MU, Knoll-Ruzicka ML, Domschke S, et al: Pancreatic enzyme replacement therapy: Comparative effects of conventional and enteric-coated
microspheric pancreatin and acid-stable fungal enzyme preparations on steatorrhea in chronic pancreatitis. Hepatogastroenterol 1985;32:97-102.
19. Friess H, et al.:Influence of high-dose pancreatic enzyme treatment on pancreatic function in healthy volunteers. Int J Pancreatol 1998;23:115-23.

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2017-10-19T07:30:02+00:00 October 19th, 2017|

2 Comments

  1. Marquis Zeise October 24, 2017 at 7:45 am - Reply

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  2. Vincent Martin October 29, 2017 at 11:44 pm - Reply

    You cleared My All Questions About Pancreatin thanks

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